1, 1, 1, 3, 3, 3-Hexamethyldisilazane

1, 1, 1, 3, 3, 3-Hexamethyldisilazane

HMDS; Bis(trimethylsilyl)amine; N,N-Bis(trimethylsilyl)amine

CAS 999-97-3

Chemical Formula HN[Si(CH3)3]2

Molecular Weight 161.39 g/mol

1,1,1,3,3,3-Hexamethyldisilazane (HMDS), also known as hexamethyldisilazane, is a chemical compound commonly used in the chemical and pharmaceutical industries, particularly for its silylating properties. While HMDS does not act as an H₂ acceptor or donor like mesitylene, its unique reactivity is crucial in applications requiring modification of organic molecules, enhancing their properties for various industrial uses.

Industrial Uses

1. Pharmaceuticals

  • Protecting Agent: It is widely used as a silylating agent in pharmaceutical synthesis. It helps protect functional groups like hydroxyl, amino, and carboxyl during chemical reactions, preventing unwanted side reactions.
  • Drug Development: In the production of active pharmaceutical ingredients (APIs), It is employed to modify molecules and improve their stability, solubility, and overall efficacy.

2. Polymers & Resins

  • Crosslinking Agent: It is sometimes used as a crosslinking agent in silicone-based polymers, contributing to the development of materials with improved mechanical properties, such as elasticity and durability.
  • Modifier in Polymer Synthesis: It can modify polymers' surface characteristics, particularly in enhancing hydrophobicity or creating non-stick surfaces in silicone-based polymers.

3. Chemical Synthesis

  • Reagent in Organic Synthesis: It is a common reagent in organic chemistry for silylation reactions. It is used to introduce trimethylsilyl (TMS) groups to molecules, which can increase volatility and stability, especially in gas chromatography and mass spectrometry.
  • Polymerization Processes: In chemical research, It is utilized to modify surfaces and initiate specific polymerization reactions. It is particularly effective in modifying surfaces to improve the properties of certain polymers.

4. Oil & Gas

  • Additive in Drilling Fluids: It may be added to drilling fluids used in the oil and gas industry to improve the efficiency of drilling processes by enhancing the fluid’s hydrophobic properties and controlling reactions with water-sensitive formations.

5. Fabric Solutions

  • Hydrophobic Treatment: It is employed as a treatment to make textiles water-repellent. This is particularly useful in the production of outdoor fabrics, protective clothing, and technical textiles where moisture resistance is critical.

Specifications

Assay ≥ 99%
Appearance Clear, colorless liquid
Odor Ammonia-like odor
Boiling Point 125-126°C (257-259°F)
Melting Point -70°C (-94°F)
Density 0.773 g/cm³ at 25°C
Solubility Reacts with water; soluble in organic solvents like hexane and ether
Viscosity 0.46 cP at 25°C
Flash Point 2°C (35.6°F) (Closed cup)

Hazard Symbols

Flammables
Flammables
Corrosives
Corrosives
Irritants/Sensitisers/Other Hazards
Irritants/Sensitisers/Other Hazards

FAQs

1. What is the current price of 1,1,1,3,3,3-Hexamethyldisilazane in India?
The price of 1,1,1,3,3,3-Hexamethyldisilazane can vary based on factors such as purity, quantity, etc. For the most accurate and competitive pricing, please contact us at +91-22-4343 2121 directly for a customized quote tailored to your needs.

2. Where can I buy 1,1,1,3,3,3-Hexamethyldisilazane in India?
You can purchase 1,1,1,3,3,3-Hexamethyldisilazane from MULTICHEM, a leading importer with a reputation for quality and reliability. We provide convenient options for bulk orders and direct shipments across India. For more details on how to place an order, please visit our website or contact our sales team.

3. What is the minimum order quantity (MOQ) for 1,1,1,3,3,3-Hexamethyldisilazane?
Our minimum order quantity (MOQ) for 1,1,1,3,3,3-Hexamethyldisilazane is designed to cater to both small-scale and large-scale needs. The MOQ depends on the packing size of the product which could range from 25 kg to 250kg.

4. How can I ensure the quality of 1,1,1,3,3,3-Hexamethyldisilazane supplied by Multichem?
We adhere to stringent quality control processes to ensure that our products meet the highest standards of purity and effectiveness. They undergo rigorous testing and quality checks to guarantee that they comply with industry specifications. We provide a Certificate of Analysis (CoA) with every shipment to ensure transparency and quality assurance.